Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Fgf1-RFP,-cre/ERT2)13AChiu
Name:	transgene insertion 13A, Ing-Ming Chiu
MGI ID:	MGI:7482681
Synonyms:	F1A-CreERT2
Transgene:	Tg(Fgf1-RFP,-cre/ERT2)13AChiu  Location: unknown
Alliance:	Tg(Fgf1-RFP,-cre/ERT2)13AChiu page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inducible, Recombinase) Mutation:    Insertion   Tg(Fgf1-RFP,-cre/ERT2)13AChiu expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Fgf1 (MGI:95515)   Mutation details: The 131.5 kb transgene consists of an RFP-IRES-CreERT2polyA expression cassette inserted into a mouse bacterial artificial chromosome (BAC) clone RP23-193N23 including Fgf1 5' UTR (127.7 kb), exon 1A, and 1B sequence containing the promoter for alternatively spliced to the first protein-coding exon 1A isoform predominantly expressed in the heart. Three founders 13A, 22A, and 25A were confirmed. Line #13A with the highest expression of Cre recombinase in the heart was chosen for all the following studies. (J:323281)

Activity:	Tissue activity of this recombinase allele
Driver:	Fgf1 (mouse) Summary of all recombinase alleles driven by Fgf1. Comparative matrix view of recombinase activities Alliance mouse Fgf1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:323281 Hsu YC, et al., Establishing F1A-CreER(T2) Mice to Trace Fgf1 Expression in Adult Mouse Cardiomyocytes. Cells. 2021 Dec 30;11(1)
All:	1 reference(s)