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Vil1em1(flpo)Lbrl
Endonuclease-mediated Allele Detail
Summary
Symbol: Vil1em1(flpo)Lbrl
Name: villin 1; endonuclease-mediated mutation 1, Stephen Liberles
MGI ID: MGI:7482596
Synonyms: Vil1-p2a-FlpO
Gene: Vil1  Location: Chr1:74448543-74474719 bp, + strand  Genetic Position: Chr1, 38.54 cM, cytoband C5
Alliance: Vil1em1(flpo)Lbrl page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Vil1em1(flpo)Lbrl expression driven by 1 gene
 
Mutation detailsCRISPR/Cas9 methodologies were used to replace the Stop codon of the mouse Vil1 gene with p2A-FlpO recombinase sequence. (J:335608)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Vil1 (mouse)
Summary of all recombinase alleles driven by Vil1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vil1 Mutation:  50 strains or lines available
References
Original:  J:335608 Hayashi M, et al., Enteroendocrine cell lineages that differentially control feeding and gut motility. Elife. 2023 Feb 22;12
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory