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Gene Expression Data
Assay Details
Assay
Reference: J:238636 Fededa JP, et al., MicroRNA-34/449 controls mitotic spindle orientation during mammalian cortex development. EMBO J. 2016 Nov 15;35(22):2386-2398
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7482535
Gene symbol: Satb2
Gene name: special AT-rich sequence binding protein 2
Antibody: anti-SATB2
Results
Specimen 3A Het: embryonic day 16.0; Mir34atm1.1Aven/Mir34a+, Mirc21tm1.1Aven/Mirc21+, Mirc34tm1.1Cxu/Mirc34+ (more )
Note: Heterozygous littermate control mice were used but the specific genotype for specimen shown was not detailed.
Structure Cell Type Level Pattern Image Note
TS24: neocortex neuron of the forebrain Present Regionally restricted 3A Het Expression in neurons of layers II-IV.
Specimen 3A KO: embryonic day 16.0; Mir34atm1.1Aven/Mir34atm1.1Aven, Mirc21tm1.1Aven/Mirc21tm1.1Aven, Mirc34tm1.1Cxu/Mirc34tm1.1Cxu (more )
Note: Double (DKO) and triple (TKO) knockout littermates were grouped in this study. The specific genotype of the specimen shown was not reported. Embryos may or may not have expressed the Mir34a wild type allele.
Structure Level Pattern Image Note
TS24: neocortex Weak Regionally restricted 3A KO Significantly reduced number of expressing cells compared to control.
Specimen EV3A SATB2 Het: embryonic day 16.0; Mir34atm1.1Aven/Mir34a+, Mirc21tm1.1Aven/Mirc21+, Mirc34tm1.1Cxu/Mirc34+ (more )
Note: Heterozygous littermate control mice were used but the specific genotype for specimen shown was not detailed.
Structure Cell Type Level Pattern Image Note
TS24: neocortex neuron of the forebrain Present Regionally restricted EV3A SATB2 Het Expression in neurons of layers II-IV.
Specimen EV3A SATB2 KO: embryonic day 16.0; Mir34atm1.1Aven/Mir34atm1.1Aven, Mirc21tm1.1Aven/Mirc21tm1.1Aven, Mirc34tm1.1Cxu/Mirc34tm1.1Cxu (more )
Note: Double (DKO) and triple (TKO) knockout littermates were grouped in this study. The specific genotype of the specimen shown was not reported. Embryos may or may not have expressed the Mir34a wild type allele.
Structure Level Pattern Image Note
TS24: neocortex Weak Regionally restricted EV3A SATB2 KO Significantly reduced number of expressing cells compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory