Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Vsx1-cre/ERT2)471Fclo
Name:	transgene insertion 471, Frederic Clotman
MGI ID:	MGI:7482341
Synonyms:	Vsx1-CreERT2BAC
Transgene:	Tg(Vsx1-cre/ERT2)471Fclo  Location: unknown
Alliance:	Tg(Vsx1-cre/ERT2)471Fclo page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Vsx1-cre/ERT2)471Fclo expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Vsx1 (MGI:1890816)   Mutation details: The transgene consists of a BAC (RP23-341J5) with 160 kb around the Vsx1 locus modified by homologous recombination in E. coli to insert the CreERT2 coding sequence at the Vsx1 translation initiation codon. Nine founder lines were obtained, and line 471 with high recombination was established and used for the studies. (J:322776)

Activity:	Tissue activity of this recombinase allele
Driver:	Vsx1 (mouse) Summary of all recombinase alleles driven by Vsx1. Comparative matrix view of recombinase activities Alliance mouse Vsx1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:322776 Baudouin C, et al., Generation and characterization of a tamoxifen-inducible Vsx1-CreER(T2) line to target V2 interneurons in the mouse developing spinal cord. Genesis. 2021 Aug;59(7-8):e23435
All:	1 reference(s)