Prf1em2(cre)Smoc
Endonuclease-mediated Allele Detail
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Symbol: |
Prf1em2(cre)Smoc |
Name: |
perforin 1 (pore forming protein); endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
MGI ID: |
MGI:7482335 |
Synonyms: |
Prf1/IRES-EGFP-T2A-Cre |
Gene: |
Prf1 Location: Chr10:61133612-61140459 bp, + strand Genetic Position: Chr10, 32.18 cM
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Alliance: |
Prf1em2(cre)Smoc page
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Allele Type: |
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Endonuclease-mediated (Recombinase, Reporter) |
Mutation: |
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Insertion
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Prf1em2(cre)Smoc expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Prf1 (MGI:97551) |
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Mutation details: Using CRISPR targeting, the IRES-EGFP-T2A-Cre sequence was inserted just before the stop codon of the Prf1.
(J:322580)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Prf1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Prf1 Mutation: |
48 strains or lines available
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Original: |
J:322580 Pan Y, et al., Inhibition of Perforin-Mediated Neurotoxicity Attenuates Neurological Deficits After Ischemic Stroke. Front Cell Neurosci. 2021;15:664312 |
All: |
1 reference(s) |
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