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Tg(Slc1a2-RHO/ADRA1,-EYFP)941Hhir
Transgene Detail
Summary
Symbol: Tg(Slc1a2-RHO/ADRA1,-EYFP)941Hhir
Name: transgene insertion 941, Hajime Hirase
MGI ID: MGI:7482225
Synonyms: strong TG
Transgene: Tg(Slc1a2-RHO/ADRA1,-EYFP)941Hhir  Location: unknown  
Alliance: Tg(Slc1a2-RHO/ADRA1,-EYFP)941Hhir page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe mouse BAC (RP23-381H22) containing Slc1a2 is modified to insert the reporter cassette immediately downstream of the Slc1a2 initiation codon. The reporter construct includes: Optoalpha;1AR (a chimeric molecule of mammalian rhodopsin and Gq-coupled alpha;1 adrenergic receptor), a YFP reporter, an WPRE site, a polyA sequence and an FRT-flanked ampicillin selection cassette. The Amp cassette was removed from the BAC clone using a flp recombinase expression plasmid. (J:333806)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:333806 Iwai Y, et al., Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement. Front Neural Circuits. 2021;15:658343
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory