Ror2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:156970 Mikels A, et al., Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling. J Biol Chem. 2009 Oct 30;284(44):30167-76
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7481218
Gene symbol:	Ror2
Gene name:	receptor tyrosine kinase-like orphan receptor 2

Antibody:	anti-Ror2 (mouse)
Detection system:	Secondary antibody coupled to horseradish peroxidase

Results

4A WT ©

Specimen 4A WT: embryonic day 13.5; Ror2^tm1Ymi/Ror2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS21: lung	Strong		4A WT
TS21: heart	Present		4A WT
TS21: metanephros	Present		4A WT
TS21: rib cartilage condensation	Present		4A WT
TS21: telencephalon	Present		4A WT
TS21: vertebral cartilage condensation	Present		4A WT
TS21: facial prominence	Present	Regionally restricted	4A WT	Expression is in the snout.

4A KO ©

Specimen 4A KO: embryonic day 13.5; Ror2^tm1Ymi/Ror2^tm1Ymi (more

)

Structure	Level	Image
TS21: facial prominence	Absent	4A KO
TS21: heart	Absent	4A KO
TS21: lung	Absent	4A KO
TS21: metanephros	Absent	4A KO
TS21: rib cartilage condensation	Absent	4A KO
TS21: telencephalon	Absent	4A KO
TS21: vertebral cartilage condensation	Absent	4A KO

4B WT ©

Specimen 4B WT: embryonic day 14.5; Ror2^tm1Ymi/Ror2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS22: lung mesenchyme	Present		4B WT	Expression was highest in the cells that surround airway epithelial cells.

4B KO ©

Specimen 4B KO: embryonic day 14.5; Ror2^tm1Ymi/Ror2^tm1Ymi (more

)

Structure	Level	Pattern	Image	Note
TS22: lung mesenchyme	Absent		4B KO

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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