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Gene Expression Data
Assay Details
Assay
Reference: J:333828 Blommers M, et al., Retinal neuroblast migration and ganglion cell layer organization require the cytoskeletal-interacting protein Mllt11. Dev Dyn. 2023 Feb;252(2):305-319
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7469654
Gene symbol: Rbpms
Gene name: RNA binding protein gene with multiple splicing
Antibody: anti-RBPMS (1832-RBPMS)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A/D: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: retina layer retinal ganglion cell Present Regionally restricted 3A , 3D Expressed in the ganglion cell layer.
Specimen 3C WT: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: retina layer retinal ganglion cell Present Regionally restricted 3C WT Expressed in the ganglion cell layer.
Specimen 3B/E: embryonic day 16.5; Mllt11tm1c(KOMP)Mbp/Mllt11tm1c(KOMP)Mbp, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Cux2tm1.1(cre)Mull/Cux2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: retina layer retinal ganglion cell Present Regionally restricted 3B , 3E Reduced cellular density in the ganglion cell layer, compared with the controls. Distinct tissue gaps were seen.
Specimen 3C cKO: embryonic day 16.5; Mllt11tm1c(KOMP)Mbp/Mllt11tm1c(KOMP)Mbp, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Cux2tm1.1(cre)Mull/Cux2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS24: retina layer retinal ganglion cell Present Regionally restricted 3C cKO Reduced cellular density in the ganglion cell layer, compared with the controls. Distinct tissue gaps were seen.
Specimen 3G/J: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: retina ganglion cell layer retinal ganglion cell Present 3G , 3J
Specimen 3I WT: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: retina ganglion cell layer retinal ganglion cell Present 3I WT
Specimen 3H/K: embryonic day 18.5; Mllt11tm1c(KOMP)Mbp/Mllt11tm1c(KOMP)Mbp, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Cux2tm1.1(cre)Mull/Cux2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: retina ganglion cell layer retinal ganglion cell Present 3K , 3H Reduced cellular density compared with the controls. Distinct tissue gaps were seen.
Specimen 3I cKO: embryonic day 18.5; Mllt11tm1c(KOMP)Mbp/Mllt11tm1c(KOMP)Mbp, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Cux2tm1.1(cre)Mull/Cux2+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: retina ganglion cell layer retinal ganglion cell Present 3I cKO Reduced cellular density compared with the controls. Distinct tissue gaps were seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory