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Gene Expression Data
Assay Details
Assay
Reference: J:333014 Wartenberg P, et al., Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain. J Neurosci. 2021 Nov 3;41(44):9177-9191
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7469647
Gene symbol: Esr1
Gene name: estrogen receptor 1 (alpha)
Antibody: anti-ERa (06-935)
Detection system: Secondary antibody
Results
Specimen 4A E12.5 male: embryonic day 12.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Level Pattern Image Note
TS20: forebrain Absent 4A E12.5 male overview , 4A E12.5 male detail No expression was seen in E12.5 embryos.

Specimen 4A E12.5 female: embryonic day 12.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Level Pattern Image Note
TS20: forebrain Absent 4A E12.5 female overview , 4A E12.5 female detail No expression was seen in E12.5 embryos.

Specimen 4A E13.5 male: embryonic day 13.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS21: preoptic area neuron of the forebrain Present Single cells 4A E13.5 male overview , 4A E13.5 male detail A few expressing cells are seen in the medial preoptic area.

Specimen 4A E13.5 female: embryonic day 13.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS21: preoptic area neuron of the forebrain Present Single cells 4A E13.5 female detail , 4A E13.5 female overview A few expressing cells are seen in the medial preoptic area.

Specimen 4A E16.5 male: embryonic day 16.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS24: medial preoptic area neuron of the forebrain Present 4A E16.5 male detail , 4A E16.5 male overview

Specimen 4A E16.5 female: embryonic day 16.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS24: medial preoptic area neuron of the forebrain Present 4A E16.5 female detail , 4A E16.5 female overview

Specimen 4A E18.5 male: embryonic day 18.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS26: medial preoptic area neuron of the forebrain Present 4A E18.5 male detail , 4A E18.5 male overview

Specimen 4A E18.5 female: embryonic day 18.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS26: medial preoptic area neuron of the forebrain Present 4A E18.5 female overview , 4A E18.5 female detail

Specimen 5 E13.5 male: embryonic day 13.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS21: preoptic area neuron of the forebrain Present Single cells 5_E13.5 male A few expressing cells are seen in the medial preoptic area.

Specimen 5 E13.5 female: embryonic day 13.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS21: preoptic area neuron of the forebrain Present Single cells 5_E13.5 female A few expressing cells are seen in the medial preoptic area.

Specimen 5 E16.5 male: embryonic day 16.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS24: medial preoptic area neuron of the forebrain Present 5_E16.5 male

Specimen 5 E16.5 female: embryonic day 16.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS24: medial preoptic area neuron of the forebrain Present 5_E16.5 female

Specimen 5 E18.5 male: embryonic day 18.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS26: medial preoptic area neuron of the forebrain Present 5_E18.5 male

Specimen 5 E18.5 female: embryonic day 18.5; Cyp19a1tm2.1(cre)Shah/Cyp19a1+, Gt(ROSA)26Sortm1(CAG-Mapt/GFP)Uboe/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Esr1; green - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS26: medial preoptic area neuron of the forebrain Present 5_E18.5 female


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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory