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Gene Expression Data
Assay Details
Assay
Reference: J:332928 Wu X, et al., Early embryonic lethality of mice lacking POLD2. Mol Reprod Dev. 2022 Dec 18;
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7469438
Gene symbol: Pold2
Gene name: polymerase (DNA directed), delta 2, regulatory subunit
Reporter: lacZ
Direct Detection
Results
Specimen 2d WM: embryonic day 7.5; Pold2tm1.1(KOMP)Vlcg/Pold2tm1.1(KOMP)Vlcg (more )
Note: Embryo fixed in 0.2% glutaraldehyde and 1% formaldehyde.
Structure Level Pattern Image Note
TS11: embryo Present 2d left

Specimen 2d section: embryonic day 7.5; Pold2tm1.1(KOMP)Vlcg/Pold2tm1.1(KOMP)Vlcg (more )
Note: Embryo fixed in 0.2% glutaraldehyde and 1% formaldehyde.
Structure Level Pattern Image Note
TS11: embryo ectoderm Present 2d right
TS11: embryo mesoderm Present 2d right
TS11: extraembryonic mesoderm Present 2d right
TS11: embryo Present Regionally restricted 2d right LacZ is detected in ectoderm and mesoderm (including extra-embryonic mesoderm); it is largely absent from the definitive endoderm and visceral endoderm.

Specimen 2e WM: embryonic day 8.5; Pold2tm1.1(KOMP)Vlcg/Pold2tm1.1(KOMP)Vlcg (more )
Note: Embryo fixed in 0.2% glutaraldehyde and 1% formaldehyde.
Structure Level Pattern Image Note
TS13: embryo Present 2e left

Specimen 2e section: embryonic day 8.5; Pold2tm1.1(KOMP)Vlcg/Pold2tm1.1(KOMP)Vlcg (more )
Note: Embryo fixed in 0.2% glutaraldehyde and 1% formaldehyde.
Structure Level Pattern Image Note
TS13: embryo ectoderm Present 2e right
TS13: embryo mesoderm Present 2e right
TS13: head Present 2e right
TS13: heart Present 2e right
TS13: embryo Present Regionally restricted 2e right LacZ is detected in ectoderm and mesoderm (including extra-embryonic mesoderm); it is largely absent from the definitive endoderm and visceral endoderm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory