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Gene Expression Data
Assay Details
Assay
Reference: J:124279 Zhang B, et al., Mice lacking sister chromatid cohesion protein PDS5B exhibit developmental abnormalities reminiscent of Cornelia de Lange syndrome. Development. 2007 Sep;134(17):3191-201
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7468965
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-TuJ1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4H: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: intestine migratory enteric neural crest cell Present Regionally restricted 4H Expression in migrating neural crest cells reaching mid-colon by E12.5.
Specimen 4I: embryonic day 12.5; Pds5btm1Jmi/Pds5btm1Jmi (more )
Structure Cell Type Level Pattern Image Note
TS20: intestine migratory enteric neural crest cell Present Regionally restricted 4I Enteric nervous system precursors fail to migrate past ileocecal junction.
Specimen 4L: embryonic day 18.5 (more )
Structure Cell Type Level Pattern Image Note
TS26: enteric nervous system enteric neuron Present Regionally restricted 4L Expression in enteric neurons colonizing entire length of bowel.
Specimen 4M: embryonic day 18.5; Pds5btm1Jmi/Pds5btm1Jmi (more )
Structure Cell Type Level Pattern Image Note
TS26: enteric nervous system enteric neuron Present Regionally restricted 4M Authors report variable degrees of abnormal innervation and ganglion formation in distal colon.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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