Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Bcl11atm1.1(cre/ERT2)Khal
Name:	BCL11 transcription factor A; targeted mutation 1.1, Walid T Khaled
MGI ID:	MGI:7468922
Synonyms:	Bcl11aCreERT2
Gene:	Bcl11a  Location: Chr11:24028056-24124123 bp, + strand  Genetic Position: Chr11, 14.41 cM
Alliance:	Bcl11atm1.1(cre/ERT2)Khal page

Germline Transmission:	Earliest citation of germline transmission: J:335215
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Bcl11atm1.1(cre/ERT2)Khal expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Bcl11a (MGI:106190)   Mutation details: The allele was generated by introducing an IRES-CreERT2-polyA-FRT-PGK-E7-Neo-polyA-FRT cassette into the 3UTR of Bcl11a locus by targeted homologous recombination in the ES cells. (J:335215)

Activity:	Tissue activity of this recombinase allele
Driver:	Bcl11a (mouse) Summary of all recombinase alleles driven by Bcl11a. Comparative matrix view of recombinase activities Alliance mouse Bcl11a gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl11a Mutation:	42 strains or lines available

Original:	J:335215 Pensa S, et al., The generation of a Bcl11a lineage tracing mouse model. bioRxiv. 2021 Jul;
All:	2 reference(s)