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Gene Expression Data
Assay Details
Assay
Reference: J:40188 Chin JR, et al., Matrix metalloproteinases regulate morphogenesis, migration and remodeling of epithelium, tongue skeletal muscle and cartilage in the mandibular arch. Development. 1997 Apr;124(8):1519-30
Assay type: RNA in situ
MGI Accession ID: MGI:7468813
Gene symbol: Mmp2
Gene name: matrix metallopeptidase 2
Probe: Mmp2 probe2
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen E12 not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: mandible primordium Present Diffuse Expression initially diffuse through mandible at E12.
Specimen E13 not shown: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: mandible Strong Regionally restricted Stronger, more restricted pattern of expression from E13 to E15.
Specimen 2A: embryonic day 14.0-15.0 (more )
Structure Level Pattern Image Note
TS22: lower jaw mesenchyme Strong Regionally restricted 2A Intense expression in mesenchyme below epithelium of oral sulcus.
TS22: tongue mesenchyme Strong Regionally restricted 2A Intense expression in immediate subepithelial layer of tongue.
TS22: oral region epithelium Trace 2A Little or no expression in epithelium of oral surface, tongue or invaginating tooth buds.
TS22: tongue epithelium Trace 2A Little or no expression in epithelium of oral surface, tongue or invaginating tooth buds.
TS22: tooth bud Trace 2A Little or no expression in epithelium of oral surface, tongue or invaginating tooth buds.
Specimen 2B: embryonic day 14.0-15.0 (more )
Structure Level Pattern Image Note
TS22: lower jaw mesenchyme Strong Regionally restricted 2B Intense expression in mesenchyme below epithelium of oral sulcus.
TS22: tongue mesenchyme Strong Regionally restricted 2B Intense expression along medial sulcus and base of the tongue in a distinct layer underlying the outer mucosal epithelium of tongue
Specimen 2C: embryonic day 14.0-15.0 (more )
Structure Level Pattern Image Note
TS22: lower jaw mesenchyme Strong Regionally restricted 2C Intense expression in osteogenic mesenchyme below oral sulcus and surrounding osteoid and Meckel's cartilage.
TS22: Meckel's cartilage Trace 2C Little or no expression in Meckel's cartilage proper.
TS22: genioglossus Trace 2C Little or no expression in genioglossus muscle.
Specimen 2D: embryonic day 14.0-15.0 (more )
Structure Level Pattern Image Note
TS22: lower jaw mesenchyme Strong Regionally restricted 2D Intense expression in osteogenic mesenchyme surrounding osteoid.
TS22: perichondrium Strong Regionally restricted 2D Intense expression in perichondrium of Meckel's cartilage and hyoid cartilage.
TS22: Meckel's cartilage Trace 2D Little or no expression in Meckel's cartilage proper.
Specimen 2E/F: embryonic day 14.0-15.0 (more )
Structure Level Pattern Image Note
TS22: lower jaw tooth mesenchyme Strong Regionally restricted 2E , 2F Intense expression in mesenchyme surrounding tooth buds.
TS22: oral region epithelium Trace 2F , 2E Little or no expression in epithelium of oral surface.
TS22: tooth bud Trace 2E , 2F Little or no expression in invaginating tooth buds.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory