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Gene Expression Data
Assay Details
Assay
Reference: J:335090 McLaughlin MT, et al., Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis. Dev Dyn. 2023 Apr;252(4):483-494
Assay type: RNA in situ
MGI Accession ID: MGI:7468631
Gene symbol: Frem1
Gene name: Fras1 related extracellular matrix protein 1
Probe: Frem1 probe
Probe preparation: RNA
Results
Specimen 1I: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: maxillary process Strong 1I Strong expression in both medial nasal process and maxillary process.
TS19: medial-nasal process Strong 1I Strong expression in both medial nasal process and maxillary process.
Specimen 1J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: maxillary process mesenchyme Present Graded 1J Expansive spatial gradients of expression in medial-nasal process and maxillary process mesenchyme.
TS19: medial-nasal process mesenchyme Present Graded 1J Expansive spatial gradients of expression in medial-nasal process and maxillary process mesenchyme.
Specimen 2A: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS18: medial-nasal process mesenchyme Present Graded 2A Spatial gradient of expression in cranial neural crest-derived mesenchyme of medial nasal process.
Specimen 2D: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS18: facial prominence mesenchyme Present Regionally restricted 2D Gradient of expression in mesenchyme of maxillary process.
Specimen 2G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: medial-nasal process mesenchyme Present Graded 2G Spatial gradient of expression in cranial neural crest-derived mesenchyme of medial nasal process.
Specimen 2J: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: mandibular process mesenchyme Present Graded 2J Gradient of expression in palatal shelf mesenchyme and mandibular process.
TS21: palatal shelf mesenchyme Present Graded 2J Gradient of expression in palatal shelf mesenchyme and mandibular process.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory