Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tacr1tm1.1(cre/GFP)Xzd
Name:	tachykinin receptor 1; targeted mutation 1, Xinzhong Dong
MGI ID:	MGI:7468609
Synonyms:	NK1R-GFP-Cre
Gene:	Tacr1  Location: Chr6:82379315-82537085 bp, + strand  Genetic Position: Chr6, 35.94 cM, cytoband D1
Alliance:	Tacr1tm1.1(cre/GFP)Xzd page

Germline Transmission:	Earliest citation of germline transmission: J:319932
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Recombinase, Reporter) Mutation:    Insertion   Tacr1tm1.1(cre/GFP)Xzd expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tacr1 (MGI:98475)   Mutation details: The allele was generated by using a homologous recombination knock-in approach. The GFP-Cre transgene was integrated into the start codon of the Tacr1 gene using two homologous arms targeting the sequences. Cre and GFP fusion protein is expressed under Tacr1 (NK1R) promotor control. (J:319932)

Activity:	Tissue activity of this recombinase allele
Driver:	Tacr1 (mouse) Summary of all recombinase alleles driven by Tacr1. Comparative matrix view of recombinase activities Alliance mouse Tacr1 gene page

In Mice Carrying this Mutation:

3 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tacr1 Mutation:	40 strains or lines available

Original:	J:319932 Xu Q, et al., Astrocytes contribute to pain gating in the spinal cord. Sci Adv. 2021 Nov 5;7(45):eabi6287
All:	1 reference(s)