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Gene Expression Data
Assay Details
Assay
Reference: J:172775 Gildea DE, et al., The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling. FASEB J. 2011 May;25(5):1596-605
Assay type: RNA in situ
MGI Accession ID: MGI:7467443
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen +/+ E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: apical ectodermal ridge Present 6_Fgf8 E10.5 +/+

Specimen XsJ/+ E10.5: embryonic day 10.5; Eif3cXs-J/Eif3c+ (more )
Structure Level Pattern Image Note
TS17: apical ectodermal ridge Present Regionally restricted 6_Fgf8 E10.5 XsJ/+ Ectopic anterior expression was observed.

Specimen +/+ E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present 6_Fgf8 E11.5 +/+

Specimen XsJ/+ E11.5: embryonic day 11.5; Eif3cXs-J/Eif3c+ (more )
Structure Level Pattern Image Note
TS19: apical ectodermal ridge Present Regionally restricted 6_Fgf8 E11.5 XsJ/+ Ectopic anterior expression was observed.

Specimen +/+ E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb Absent 6_Fgf8 E12.5 +/+

Specimen XsJ/+ E12.5: embryonic day 12.5; Eif3cXs-J/Eif3c+ (more )
Structure Level Pattern Image Note
TS20: limb Absent 6_Fgf8 E12.5 XsJ/+


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory