Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Flrt3tm4(cre/ERT2)Kln
Name:	fibronectin leucine rich transmembrane protein 3; targeted mutation 3, Rudiger Klein
MGI ID:	MGI:7467420
Synonyms:	Flrt3Cre/ERT2
Gene:	Flrt3  Location: Chr2:140500118-140513396 bp, - strand  Genetic Position: Chr2, 69.2 cM
Alliance:	Flrt3tm4(cre/ERT2)Kln page

Germline Transmission:	Earliest citation of germline transmission: J:319358
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Flrt3tm4(cre/ERT2)Kln expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Flrt3 (MGI:1918686)   Mutation details: The targeting construct inserted the CreERT2 sequence, an SV40 polyadenylation signal, and a loxP-flanked neo cassette into exon 3 of the Flrt3 gene via homologous recombination in ES cells. (J:319358)

Activity:	Tissue activity of this recombinase allele
Driver:	Flrt3 (mouse) Summary of all recombinase alleles driven by Flrt3. Comparative matrix view of recombinase activities Alliance mouse Flrt3 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Flrt3 Mutation:	44 strains or lines available

Original:	J:319358 Ruff T, et al., FLRT3 Marks Direction-Selective Retinal Ganglion Cells That Project to the Medial Terminal Nucleus. Front Mol Neurosci. 2021;14:790466
All:	1 reference(s)