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Slc17a6tm1.1(flpo)Mgmj
Targeted Allele Detail
Summary
Symbol: Slc17a6tm1.1(flpo)Mgmj
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 1.1, Martin G Myers, Jr
MGI ID: MGI:7467070
Synonyms: Slc17a6FlpO
Gene: Slc17a6  Location: Chr7:51271754-51320867 bp, + strand  Genetic Position: Chr7, 32.78 cM, cytoband B4
Alliance: Slc17a6tm1.1(flpo)Mgmj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:317381
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Slc17a6tm1.1(flpo)Mgmj expression driven by 1 gene
 
Mutation detailsThe targeting construct containing IRES-FlpO-a LoxP-flanked neomycin selection cassette was targeted 3 bp downstream of the stop codon of the Slc17a6 gene in ES cells. Targeted ES clones were expanded and injected into blastocysts and chimeric offspring were then bred to confirm germline transmission of the allele. The neomycin selection cassette was removed by breeding to the E2A-Cre deleter strain. (J:317381)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc17a6 (mouse)
Summary of all recombinase alleles driven by Slc17a6.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc17a6 Mutation:  59 strains or lines available
References
Original:  J:317381 Sabatini PV, et al., tTARGIT AAVs mediate the sensitive and flexible manipulation of intersectional neuronal populations in mice. Elife. 2021 Mar 11;10:e66835
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory