Tg(Grik4-Lgi1)#Mafu
Transgene Detail
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| Symbol: |
Tg(Grik4-Lgi1)#Mafu |
| Name: |
transgene insertion, Masaki Fukata |
| MGI ID: |
MGI:7466732 |
| Synonyms: |
KA1-Lgi1 |
| Transgene: |
Tg(Grik4-Lgi1)#Mafu Location: unknown
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| Alliance: |
Tg(Grik4-Lgi1)#Mafu page
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| Strain of Origin: |
(C57BL/6 X DBA/2)F1 x C57BL/6
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| Transgene Type: |
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Transgenic (Epitope tag, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Grik4-Lgi1)#Mafu expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| rat |
Lgi1 (252892) |
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mouse promoter, rat cDNA with C-terminal FLAG and 6xHis tags |
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Mutation details: The transgene insert comprises mouse BAC RP23-353O19 where the rat Lgi1 cDNA (with sequence for a C-terminal FLAG tag and 6xHis tag inserted immediately upstream of the stop codon) and a kanamycin resistance gene were inserted immediately downstream of the Lgi1 ATG translation start site.
(J:328338)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:328338 Yokoi N, et al., 14-3-3 proteins stabilize LGI1-ADAM22 levels to regulate seizure thresholds in mice. Cell Rep. 2021 Dec 14;37(11):110107 |
| All: |
1 reference(s) |
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Analysis Tools
