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Gene Expression Data
Assay Details
Assay
Reference: J:224948 Lin C, et al., A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13
Assay type: Western blot
MGI Accession ID: MGI:7466505
Gene symbol: Stk3
Gene name: serine/threonine kinase 3
Antibody: anti-MST2
Results
Image: S2D MST2 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Genetic BackgroundMutant Allele(s)Sex Note
1 P24 TS28: lung Present involves: 129S/SvEv * C57BL/6 Not Specified
2 P24 TS28: lung Present involves: 129S/SvEv * C57BL/6 Not Specified
3 P24 TS28: lung Present involves: 129S/SvEv * C57BL/6 Not Specified
4 P24 TS28: lung Weak involves: 129S/SvEv * C57BL/6 Shhtm1(EGFP/cre)Cjt/Shh+, Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy, Wwtr1tm1.1Eno/Wwtr1+, Yap1tm1.1Eno/Yap1+Not Specified Conditional mutant.
5 P24 TS28: lung Weak involves: 129S/SvEv * C57BL/6 Shhtm1(EGFP/cre)Cjt/Shh+, Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy, Wwtr1tm1.1Eno/Wwtr1+, Yap1tm1.1Eno/Yap1+Not Specified Conditional mutant.
6 P24 TS28: lung Weak involves: 129S/SvEv * C57BL/6 Shhtm1(EGFP/cre)Cjt/Shh+, Stk3tm1Yy/Stk3tm1Yy, Stk4tm1.1Yy/Stk4tm1.1Yy, Wwtr1tm1.1Eno/Wwtr1+, Yap1tm1.1Eno/Yap1+Not Specified Conditional mutant.
Notes:
(a) Reduction in protein levels in the mutant was apparent despite rescue of neonatal lethality and lung phenotypes by removing one copy of Yap1 and Taz/Wwtr1.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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