Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Cdh2tm1(cre/ERT2)Gcr
Name:	cadherin 2; targeted mutation 1, Gerhard Christofori
MGI ID:	MGI:7466159
Synonyms:	Cdh2tm1(cre/ERT2)Gcr
Gene:	Cdh2  Location: Chr18:16721934-16942303 bp, - strand  Genetic Position: Chr18, 10.1 cM
Alliance:	Cdh2tm1(cre/ERT2)Gcr page

Germline Transmission:	Earliest citation of germline transmission: J:316041
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Cdh2tm1(cre/ERT2)Gcr expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Cdh2 (MGI:88355)   Mutation details: Using ES cell electroporation and homologous recombination, a targeting vector encoding for Cre-ERT2-RPA (rabbit beta-globin gene polyadenylation signal) was targeted to the Cdh2 locus. (J:316041)

Activity:	Tissue activity of this recombinase allele
Driver:	Cdh2 (mouse) Summary of all recombinase alleles driven by Cdh2. Alliance mouse Cdh2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdh2 Mutation:	50 strains or lines available

Original:	J:316041 Luond F, et al., Distinct contributions of partial and full EMT to breast cancer malignancy. Dev Cell. 2021 Nov 23;
All:	1 reference(s)