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Tg(MMTV-flpo)11Gcr
Transgene Detail
Summary
Symbol: Tg(MMTV-flpo)11Gcr
Name: transgene insertion 11, Gerhard Christofori
MGI ID: MGI:7466141
Transgene: Tg(MMTV-flpo)11Gcr  Location: unknown  
Alliance: Tg(MMTV-flpo)11Gcr page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(MMTV-flpo)11Gcr expression driven by 1 gene
 
Mutation detailsThe codon-optimized Flp (Flpo) gene was placed under the control of the MMTV LTR promoter. Two funder lines (9 and 11) with high flpo activity were identified. One line (line 9) with more restricted flpo activity was established and used for the studies. (J:335073)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: MMTV (virus)
Summary of all recombinase alleles driven by MMTV.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:335073 Luond F, et al., A Transgenic MMTV-Flippase Mouse Line for Molecular Engineering in Mammary Gland and Breast Cancer Mouse Models. J Mammary Gland Biol Neoplasia. 2019 Mar;24(1):39-45
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory