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Gene Expression Data
Assay Details
Assay
Reference: J:184591 Aoyama M, et al., Spatial Restriction of Bone Morphogenetic Protein Signaling in Mouse Gastrula through the mVam2-Dependent Endocytic Pathway. Dev Cell. 2012 Jun 12;22(6):1163-75
Assay type: RNA in situ
MGI Accession ID: MGI:7464811
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4 Bmp4 E6.5 WT: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: extraembryonic component Present Regionally restricted 4_Bmp4 E6.5 WT Expression in extraembryonic mesoderm.

Specimen 4 Bmp4 E6.5 -/-: embryonic day 6.5; Vps41tm1.1Ywd/Vps41tm1.1Ywd (more )
Structure Level Pattern Image Note
TS9: extraembryonic component Present Regionally restricted 4_Bmp4 E6.5 -/- Expression localized more distally than in wild type.

Specimen 4 Bmp4 E7.5 WT: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: extraembryonic mesoderm Present 4_Bmp4 E7.5 WT
TS11: embryo Present Regionally restricted 4_Bmp4 E7.5 WT Expression in proximal region of embryo,

Specimen 4 Bmp4 E7.5 -/-: embryonic day 7.5; Vps41tm1.1Ywd/Vps41tm1.1Ywd (more )
Structure Level Pattern Image Note
TS11: extraembryonic mesoderm Present Regionally restricted 4_Bmp4 E7.5 -/- Expression localized more distally than in wild type.
TS11: embryo Present Regionally restricted 4_Bmp4 E7.5 -/- Expression in proximal region of embryo, similar to that of wild type.

Specimen 4 Bmp4 E8.5 -/-: embryonic day 8.5; Vps41tm1.1Ywd/Vps41tm1.1Ywd (more )
Structure Level Pattern Image Note
TS13: extraembryonic mesenchyme Present Regionally restricted 4_Bmp4 E8.5 -/- Expression localized more distally than in wild type.
TS13: embryo Present Regionally restricted 4_Bmp4 E8.5 -/- Expression in proximal region of embryo.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory