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Gene Expression Data
Assay Details
Assay
Reference: J:226036 Maddala R, et al., Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Dev Biol. 2015 Oct 1;406(1):74-91
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7464646
Gene symbol: Rap1a
Gene name: RAS-related protein 1a
Antibody: Anti-Rap1
Detection system: Secondary antibody coupled to Alexa Fluor 594
Assay notes: The specificity of the antibody used was not detailed; both family members have been annotated.
Results
Specimen 2C E11.5 WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 2C middle WT
TS19: lens vesicle epithelium Present 2C middle WT

Specimen 2C E11.5 cKO: embryonic day 11.5; Rap1atm1Morz/Rap1atm1Morz, Rap1btm1Morz/Rap1btm1Morz, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: lens vesicle Present 2C middle cKO Reduced expression compared with the control.
TS19: lens vesicle epithelium Present 2C middle cKO Reduced expression compared with the control.

Specimen 2C E17.5 WT: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lens Present 2C lower WT
TS25: lens epithelium Present 2C lower WT

Specimen 2C E17.5 cKO: embryonic day 17.5; Rap1atm1Morz/Rap1atm1Morz, Rap1btm1Morz/Rap1btm1Morz, Tg(Pax6-cre,GFP)1Pgr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: lens Present 2C lower cKO Reduced expression compared with the control.
TS25: lens epithelium Present 2C lower cKO Reduced expression compared with the control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory