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Gene Expression Data
Assay Details
Assay
Reference: J:173287 Long JE, et al., Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
Assay type: RNA in situ
MGI Accession ID: MGI:7464511
Gene symbol: Drd2
Gene name: dopamine receptor D2
Probe: D2R cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Table 4 data was incorporated into Fig. 7 samples, as per the text.
Results
Specimen 6d: embryonic day 15.5 (more )
Note: littermate control; the genetic background of the specimen is either +/+ or +/-
Structure Level Pattern Image Note
TS23: corpus striatum Present Regionally restricted 6d Expression marks the striatal differentiated state.
Specimen 6d': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: corpus striatum Weak Regionally restricted 6d' Expression was decreased in the striatum. Residual expression was seen in superficial parts of the striatal mantle.
Specimen 7j: embryonic day 15.5 (more )
Note: littermate control; the genetic background of the specimen is either +/+ or +/-
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present 7j
TS23: telencephalon septum Present 7j
Specimen 7j': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence mantle zone Weak Regionally restricted 7j'
TS23: lateral ganglionic eminence subventricular zone Absent 7j'
TS23: lateral ganglionic eminence ventricular zone Absent 7j'
TS23: telencephalon septum Present Regionally restricted 7j' Expression was unchanged in the mantle zone. It was undetectable in the ventricular zone and subventricular zone.
Specimen 7j'': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: telencephalon septum Present Regionally restricted 7j'' Expression was unchanged in the mantle zone. It was undetectable in the ventricular zone and subventricular zone.
TS23: lateral ganglionic eminence mantle zone Present 7j'' Expression was unchanged in the mantle zone.
TS23: lateral ganglionic eminence subventricular zone Absent 7j''
TS23: lateral ganglionic eminence ventricular zone Absent 7j''
Specimen 7j''': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And, Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence mantle zone Weak 7j''' Expression was severely decreased in the mantle zone.
TS23: lateral ganglionic eminence subventricular zone Absent 7j'''
TS23: lateral ganglionic eminence ventricular zone Absent 7j'''
TS23: telencephalon septum Weak Regionally restricted 7j''' Expression was severely decreased in the mantle zone. It was undetectable in the ventricular zone and subventricular zone.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
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