About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:173287 Long JE, et al., Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. J Comp Neurol. 2009 Feb 1;512(4):556-72
Assay type: RNA in situ
MGI Accession ID: MGI:7464503
Gene symbol: Tle4
Gene name: transducin-like enhancer of split 4
Probe: Tle4 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5w: embryonic day 15.5 (more )
Note: littermate control; the genetic background of the specimen is either +/+ or +/-
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence mantle zone Strong 5w
TS23: lateral ganglionic eminence subventricular zone Strong 5w

Specimen 5w': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence mantle zone Strong Regionally restricted 5w' Expression remained strong in the dorsal and ventral lateral ganglionic eminence in the mutant.
TS23: lateral ganglionic eminence subventricular zone Strong Regionally restricted 5w' Expression remained strong in the dorsal and ventral lateral ganglionic eminence in the mutant.

Specimen S2l: embryonic day 15.5 (more )
Note: littermate control; the genetic background of the specimen is either +/+ or +/-
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present S2l
TS23: telencephalon septum Present S2l

Specimen S2l': embryonic day 15.5; Del(2Dlx1-Dlx2)1Jlr/Del(2Dlx1-Dlx2)1Jlr (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence mantle zone Present S2l' Expression was unchanged in the subventricular zone and mantle zone.
TS23: lateral ganglionic eminence subventricular zone Present S2l' Expression was unchanged in the subventricular zone and mantle zone.
TS23: lateral ganglionic eminence ventricular zone Absent S2l'
TS23: telencephalon septum Present Regionally restricted S2l' Expression was unchanged in the ventricular zone, subventricular zone, and mantle zone.

Specimen S2l'': embryonic day 15.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence mantle zone Present S2l'' Expression was unchanged in the mantle zone.
TS23: lateral ganglionic eminence subventricular zone Weak Regionally restricted S2l'' Expression was severely decreased in the ventral subventricular zone.
TS23: lateral ganglionic eminence ventricular zone Absent S2l''
TS23: telencephalon septum Present Regionally restricted S2l'' Expression was increased in the ventricular zone and subventricular zone. Expression was severely decreased in the mantle zone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
09/30/2025
MGI 6.24
The Jackson Laboratory