Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Ddx4em1(icre)Jobo
Name:	DEAD box helicase 4; endonuclease-mediated mutation 1, Josephine Bowles
MGI ID:	MGI:7464282
Synonyms:	Ddx4Cre, Ddx4iCreJoBo, Ddx4-P2A-iCre
Gene:	Ddx4  Location: Chr13:112734867-112789009 bp, - strand  Genetic Position: Chr13, 63.87 cM
Alliance:	Ddx4em1(icre)Jobo page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Recombinase) Mutation:    Insertion   Ddx4em1(icre)Jobo expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Ddx4 (MGI:102670)     Using CRISPR/CAS9, the P2A-iCre cassette was inserted into the 3' of the Ddx4 gene. (J:334521)

Activity:	Tissue activity of this recombinase allele
Driver:	Ddx4 (mouse) Summary of all recombinase alleles driven by Ddx4. Comparative matrix view of recombinase activities Alliance mouse Ddx4 gene page

In Mice Carrying this Mutation:

18 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ddx4 Mutation:	58 strains or lines available

Original:	J:334521 Burnet G, et al., Generation and characterization of a Ddx4-iCre transgenic line for deletion in the germline beginning at genital ridge colonization. Genesis. 2023 Mar;61(1-2):e23511
All:	1 reference(s)