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Gene Expression Data
Assay Details
Assay
Reference: J:334528 Zheng G, et al., SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice. Cell Death Dis. 2023 Apr 6;14(4):249
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7464107
Gene symbol: Kiss1
Gene name: KiSS-1 metastasis-suppressor
Antibody: anti-KISS-1 (sc-18134)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4F SCAP+/+: embryonic day 14.5; Tg(Tagln-cre)1Her/0 (more )
Note: Littermate control; embryo might carry the Cre transgene.
Structure Level Pattern Image Note
TS22: dorsal aorta Present 4F SCAP+/+ Merge inset , 4F SCAP+/+ KISS-1 , 4F SCAP+/+ Merge
Specimen 4F SCAPfl/fl: embryonic day 14.5; Scaptm1Mbjg/Scaptm1Mbjg, Tg(Tagln-cre)1Her/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: dorsal aorta Strong 4F SCAPfl/fl Merge inset , 4F SCAPfl/fl Merge , 4F SCAPfl/fl KISS-1 More highly expressed in homozygous vessels than in wild type vessels.
Specimen S2D SCAP+/+: embryonic day 14.5; Tg(Tagln-cre)1Her/0 (more )
Structure Level Pattern Image Note
TS22: extraembryonic vascular system Present S2D SCAP+/+
Specimen S2D SCAPfl/fl: embryonic day 14.5; Scaptm1Mbjg/Scaptm1Mbjg, Tg(Tagln-cre)1Her/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: extraembryonic vascular system Strong S2D SCAPfl/fl Expression significantly upregulated in embryonic placenta compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory