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Tg(Rr28-LacZ)cDdp
Transgene Detail
Summary
Symbol: Tg(Rr28-LacZ)cDdp
Name: transgene insertion c, Dimitrina D Pravtcheva
MGI ID: MGI:7462657
Transgene: Tg(Rr28-LacZ)cDdp  Location: unknown  
Alliance: Tg(Rr28-LacZ)cDdp page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA 17 kb genomic fragment containing mouse Igf2 was modified by replacing the coding region (exons 4, 5, and a 5' portion of exon 6) with the LacZ reporter gene. A small 5' fragment of the noncoding region of the Igf2 exon 1 was also left out of this construct. A 7 kb genomic fragment containing the mouse Igf2/H19 enhancer sequences (Rr28) from downstream of H19 was placed downstream of the Igf2-LacZ construct. (J:90325)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:90325 Wise TL, et al., Perinatal lethality in H19 enhancers-Igf2 transgenic mice. Mol Reprod Dev. 1997 Oct;48(2):194-207
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory