Gene Expression Data
Assay Details
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Assay
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Reference:
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J:187163
Chen TR, et al., Generation and characterization of Tmeff2 mutant mice. Biochem Biophys Res Commun. 2012 Aug 24;425(2):189-94
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:7462382
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Gene symbol:
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Tmeff2
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Gene name:
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transmembrane protein with EGF-like and two follistatin-like domains 2
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Reporter:
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alkaline phosphatase
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Direct Detection
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Results
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Specimen
2A +/-:
embryonic day 12.5; Tmeff2tm1Fawa/Tmeff2 +
(more  )
Specimen
2A +/-:
(close  )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: brain |
Present |
Non-Uniform |
2A +/-
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Expression was stronger in some regions.
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Specimen
2A -/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2tm1Fawa
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: brain |
Present |
Non-Uniform |
2A -/-
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Expression in this mutant is similar to heterozygotes.
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Specimen
2B +/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2+
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Age:
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postnatal day 15
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: brain |
Present |
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2B +/-
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Specimen
2B -/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2tm1Fawa
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Age:
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postnatal day 15
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: brain |
Present |
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2B -/-
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Expression in this mutant is the same as in heterozygotes.
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Specimen
2C +/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2+
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Specimen
2C -/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2tm1Fawa
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Specimen
2D +/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2+
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: vibrissa |
Present |
Regionally restricted |
2D +/-
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Expression is in axon projections and innervations.
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Specimen
2D -/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2tm1Fawa
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: vibrissa |
Present |
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2D -/-
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Expression in this mutant is the same as in heterozygotes.
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Specimen
2E +/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2+
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: stomach |
enteric neuron |
Present |
Regionally restricted |
2E +/- bottom
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2E +/- top
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Expression is in enteric neurons.
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Specimen
2E -/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2tm1Fawa
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: stomach |
enteric neuron |
Present |
Regionally restricted |
2E -/- bottom
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2E -/- top
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Expression in this mutant is the same as in heterozygotes.
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Specimen
2F +/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2+
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: intestine |
enteric neuron |
Present |
Regionally restricted |
2F +/- top
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2F +/- bottom
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Expression is in enteric neurons.
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Specimen
2F -/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2tm1Fawa
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: intestine |
enteric neuron |
Present |
Regionally restricted |
2F -/- top
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2F -/- bottom
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Expression in this mutant is the same as in heterozygotes.
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Specimen
4B +/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2+
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: white fat |
white adipocyte |
Strong |
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4B +/-
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Specimen
4B -/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2tm1Fawa
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Age:
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postnatal day 10
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: white fat |
white adipocyte |
Strong |
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4B -/-
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This mutant has reduced white fat mass.
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Specimen
S1A +/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2+
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Age:
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postnatal
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Sex:
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Male
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Type:
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section
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Specimen
S1A -/-:
(close )
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: prostate gland |
Present |
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S1A -/-
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Expression in this mutant is the same as in heterozygotes.
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Specimen
S3C:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2+
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Specimen
S3D:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2tm1Fawa
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Specimen
S3G:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2+
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: liver |
Present |
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S3G
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Specimen
S3H:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tmeff2tm1Fawa/Tmeff2tm1Fawa
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: liver |
Absent |
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S3H
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Analysis Tools