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Gene Expression Data
Assay Details
Assay
Reference: J:277247 Vetrivel S, et al., Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia. Exp Eye Res. 2019 Apr 13;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7461918
Gene symbol: Pitx3
Gene name: paired-like homeodomain transcription factor 3
Antibody: Anti-Pitx3 (N-20) sc-19307X
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 8A C3H E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 8A C3H E11.5
Specimen 8A Aey69 E11.5: embryonic day 11.5; Gja8Aey69/Gja8Aey69, H3c14Aey69/H3c14Aey69 (more )
Structure Level Pattern Image Note
TS19: lens vesicle Present 8A Aey69 E11.5 No major change in distribution of expression compared to wild type.
Specimen 8A C3H E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle epithelium Present 8A C3H E12.5 Expression limited to future lens epithelium.
Specimen 8A Aey69 E12.5: embryonic day 12.5; Gja8Aey69/Gja8Aey69, H3c14Aey69/H3c14Aey69 (more )
Structure Level Pattern Image Note
TS20: lens vesicle Weak Widespread 8A Aey69 E12.5 Expression diminished in shrinking lens, distributed all over lens area.
Specimen 8A C3H E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lens epithelium Present 8A C3H E13.5 Expression limited to future lens epithelium.
Specimen 8A Aey69 E13.5: embryonic day 13.5; Gja8Aey69/Gja8Aey69, H3c14Aey69/H3c14Aey69 (more )
Structure Level Pattern Image Note
TS21: lens Weak Widespread 8A Aey69 E13.5 Expression diminished in shrinking lens, distributed all over lens area.
Specimen 8A C3H E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lens epithelium Present 8A C3H E14.5 Expression limited to future lens epithelium.
Specimen 8A Aey69 E14.5: embryonic day 14.5; Gja8Aey69/Gja8Aey69, H3c14Aey69/H3c14Aey69 (more )
Structure Level Pattern Image Note
TS22: lens Weak Widespread 8A Aey69 E14.5 Expression diminished in shrinking lens, distributed all over lens area.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory