Gene Expression Data
Assay Details
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Assay
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Reference:
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J:242353
Pichery M, et al., PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier. Hum Mol Genet. 2017 May 15;26(10):1787-1800
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7461584
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Gene symbol:
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Flg
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Gene name:
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filaggrin
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Antibody:
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Anti-Filaggrin
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Assay notes:
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Fixation was with 4% formalin.
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Results
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Specimen
2B Filaggrin WT:
embryonic day 18.5
(more  )
Specimen
2B Filaggrin WT:
(close  )
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Genetic Background:
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involves: C57BL/6N
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: epidermis |
Present |
Regionally restricted |
S4B Filaggrin WT
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Expression in keratohyaline granules.
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Specimen
2B Filaggrin tm1a:
(close )
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: epidermis |
Weak |
Regionally restricted |
S4B Filaggrin tm1a
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Authors report decreased expression.
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Analysis Tools
