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Gene Expression Data
Assay Details
Assay
Reference: J:242353 Pichery M, et al., PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier. Hum Mol Genet. 2017 May 15;26(10):1787-1800
Assay type: Western blot
MGI Accession ID: MGI:7461578
Gene symbol: Flg
Gene name: filaggrin
Antibody: Anti-Filaggrin
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 2C FLG
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
WT E18.5 TS26: epidermis Present involves: C57BL/6N Not Specified
WT E18.5 TS26: epidermis Present involves: C57BL/6N Not Specified
WT E18.5 TS26: epidermis Present involves: C57BL/6N Not Specified
WT E18.5 TS26: epidermis Present involves: C57BL/6N Not Specified
Pnpla1 tm1a E18.5 TS26: epidermis Weak (a) B6NTac;B6N-Atm1Brd Pnpla1tm1a(KOMP)Wtsi/Ics Pnpla1tm1a(KOMP)Wtsi/Pnpla1tm1a(KOMP)WtsiNot Specified
Pnpla1 tm1a E18.5 TS26: epidermis Weak (a) B6NTac;B6N-Atm1Brd Pnpla1tm1a(KOMP)Wtsi/Ics Pnpla1tm1a(KOMP)Wtsi/Pnpla1tm1a(KOMP)WtsiNot Specified
Pnpla1 tm1a E18.5 TS26: epidermis Weak (a) B6NTac;B6N-Atm1Brd Pnpla1tm1a(KOMP)Wtsi/Ics Pnpla1tm1a(KOMP)Wtsi/Pnpla1tm1a(KOMP)WtsiNot Specified
Pnpla1 tm1a E18.5 TS26: epidermis Weak (a) B6NTac;B6N-Atm1Brd Pnpla1tm1a(KOMP)Wtsi/Ics Pnpla1tm1a(KOMP)Wtsi/Pnpla1tm1a(KOMP)WtsiNot Specified
Notes:
(a) Authors report decreased expression compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory