Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Tyrp1-cre/ERT2)1Jwk
Name:	transgene insertion 1, Jin Woo Kim
MGI ID:	MGI:7460347
Transgene:	Tg(Tyrp1-cre/ERT2)1Jwk  Location: unknown
Alliance:	Tg(Tyrp1-cre/ERT2)1Jwk page

Strain of Origin:

C57BL/6J

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Tyrp1-cre/ERT2)1Jwk expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Tyrp1 (MGI:98881)   Mutation details: A DNA fragment encompassing the Tyrp1 promoter region was cloned into a vector containing the cre/ERT2 sequence. The resulting 7.3 kb construct was purified for microinjection into oocytes. (J:314167)

Activity:	Tissue activity of this recombinase allele
Driver:	Tyrp1 (mouse) Summary of all recombinase alleles driven by Tyrp1. Comparative matrix view of recombinase activities Alliance mouse Tyrp1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:314167 Lim S, et al., mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Muller glia. Elife. 2021 Oct 22;10:e70079
All:	1 reference(s)