Gene Expression Data
Assay Details
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Assay
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Reference:
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J:261219
McWilliams TG, et al., TNF superfamily member APRIL enhances midbrain dopaminergic axon growth and contributes to the nigrostriatal projection in vivo. Exp Neurol. 2017 Dec;298(Pt A):97-103
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7460332
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Gene symbol:
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Th
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Gene name:
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tyrosine hydroxylase
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Antibody:
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anti-TH (#AB152)
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Detection system:
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Secondary antibody coupled to Alexa Fluor 647
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Assay notes:
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Samples were immunolabeled following iDISCO clearing.
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Results
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Specimen
4A +/+:
embryonic day 14.0
(more  )
Specimen
4A +/+:
(close  )
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Genetic Background:
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involves: 129S4/SvJae * CD-1
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Age:
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embryonic day 14.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
4A -/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * CD-1
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Mutant Allele(s):
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Tnfsf13tm1Geha/Tnfsf13tm1Geha
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Age:
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embryonic day 14.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: superior cervical ganglion |
Present |
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4A -/-
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Expression appeared similar to the wild type.
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| TS22: brain |
Present |
Regionally restricted |
4A -/-
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Staining of the dopaminergic projection from the ventral midbrain to the striatum was more prominent in the wild type compared with the mutant.
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Analysis Tools
