Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Sox2-flpo)#Mhem
Name:	transgene insertion, Myriam Hemberger
MGI ID:	MGI:7460314
Synonyms:	Sox2-Flp, Sox2-FlpO
Transgene:	Tg(Sox2-flpo)#Mhem  Location: unknown
Alliance:	Tg(Sox2-flpo)#Mhem page

Strain of Origin:

DBA x C57BL/6

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Sox2-flpo)#Mhem expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Sox2 (MGI:98364)   Mutation details: This transgene expresses FlpO recombinase under the control of a mouse Sox2 promoter contained in a ~13.7 kb genomic fragment encompassing the Sox2. Two founder lines (1.27 and 4.2.28) were established and used in further study. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:333799)

Activity:	Tissue activity of this recombinase allele
Driver:	Sox2 (mouse) Summary of all recombinase alleles driven by Sox2. Comparative matrix view of recombinase activities Alliance mouse Sox2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:333799 Radford BN, et al., Defects in placental syncytiotrophoblast cells are a common cause of developmental heart disease. Nat Commun. 2023 Mar 1;14(1):1174
All:	1 reference(s)