Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Npr3em2(scre/ERT2)Bzsh
Name:	natriuretic peptide receptor 3; endonuclease-mediated mutation 2, Bin Zhou
MGI ID:	MGI:7451372
Synonyms:	Npr3-sCreER
Gene:	Npr3  Location: Chr15:11839982-11907287 bp, - strand  Genetic Position: Chr15, 5.83 cM
Alliance:	Npr3em2(scre/ERT2)Bzsh page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Npr3em2(scre/ERT2)Bzsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Npr3 (MGI:97373)   Mutation details: Using the CRISPR/Cas9 technology, a cDNA encoding sCre (self-cleaving cre) fused to ERT2 followed by the Woodchuck Post-transcriptional regulatory element and a polyadenylation sequence was inserted in frame with the translational start codon of the Npr3 gene. (J:309164)

Activity:	Tissue activity of this recombinase allele
Driver:	Npr3 (mouse) Summary of all recombinase alleles driven by Npr3. Alliance mouse Npr3 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npr3 Mutation:	47 strains or lines available

Original:	J:309164 Tian X, et al., Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation. EMBO J. 2020 Feb 17;39(4):e102675
All:	1 reference(s)