Antibody:

anti-Vegfr-2 (ab2349)

Structure	Level	Pattern	Image	Note
TS22: lung	Present		4a VEGFR2 WT

Structure	Level	Pattern	Image	Note
TS22: lung	Trace	Regionally restricted	4a VEGFR2 KO	Authors report expression almost absent. Liminted staining appear to be cell fragments of necrotic vessle wall endothelial cells.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: liver vascular element	lung microvascular endothelial cell	Strong	Regionally restricted	4b VEGFR2 WT	Strong expression in pulmonary vascular endothelial cells lining surfaces of lung vasculature.

Structure	Level	Pattern	Image	Note
TS22: lung vascular element	Trace	Regionally restricted	4b VEGFR2 KO	Limited staining appear to be cell fragments of necrotic vessel wall endothelial cells.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: bronchiole epithelium	epithelial cell of tracheobronchial tree	Weak	Regionally restricted	4c VEGFR2 WT	Faint expression in epithelial cells in bronchioles.

Structure	Level	Pattern	Image	Note
TS22: bronchiole	Trace	Regionally restricted	4c VEGFR2 KO	Authors report bronchioles are smaller and/or degraded. Lung appears to be fragmenting along the paths of failed vessels.

Structure	Level	Pattern	Image	Note
TS22: liver	Present		4d VEGFR2 WT

Structure	Level	Pattern	Image	Note
TS22: liver	Trace	Regionally restricted	4d VEGFR2 KO	Authors report expression almost absent. Liminted staining appear to be cell fragments of necrotic vessle wall endothelial cells.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: liver vascular element	endothelial cell of hepatic sinusoid	Present		4e VEGFR2 WT

Structure	Level	Pattern	Image	Note
TS22: liver	Trace	Regionally restricted	4e VEGFR2 KO	Authors report expression almost absent. Liminted staining appear to be cell fragments of necrotic vessle wall endothelial cells.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: heart blood vessel	cardiac blood vessel endothelial cell	Present	Regionally restricted	5a VEGFR2 WT	Expression in endothelial cells of capillaries and larger vessels.

Structure	Level	Pattern	Image	Note
TS22: heart	Trace	Regionally restricted	5a VEGFR2 KO

Structure	Cell Type	Level	Pattern	Image	Note
TS22: heart blood vessel	capillary endothelial cell	Present	Regionally restricted	5b VEGFR2 WT	Expression in myocardium capillaries.

Structure	Level	Pattern	Image	Note
TS22: cardiac muscle tissue	Trace	Regionally restricted	5b VEGFR2 KO	Authors report missing myocardium capillaries. Staining in broken circles and lines of misshapen endothelial cells and endothelial cell fragments.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: coronary artery	endothelial cell of coronary artery	Present		5c VEGFR2 WT	Expression in intact coronary vessel.

Structure	Level	Pattern	Image	Note
TS22: heart	Trace	Regionally restricted	5c VEGFR2 KO	Authors report degrading coronary vessel beneath epicardium.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: endocardial lining	endocardial cell	Present	Regionally restricted	5e VEGFR2 WT	Expression in intact epithelial cells in endocardium.

Structure	Level	Pattern	Image	Note
TS22: endocardial lining	Trace	Regionally restricted	5e VEGFR2 KO	Authors report degraded epithelial cells.

Structure	Level	Pattern	Image	Note
TS22: heart	Trace		S4b VEGFR2

Structure	Level	Pattern	Image	Note
TS22: heart	Trace	Regionally restricted	S4b VEGFR2 inset	Authors report cell fragments and phagocytosis of endothelial cells.

Structure	Cell Type	Level	Pattern	Image	Note
TS22: vertebra	chondrocyte	Present		S4c