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Gene Expression Data
Assay Details
Assay
Reference: J:195901 Ehlen H, Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res. 2013;28(2):246-59
Assay type: RNA in situ
MGI Accession ID: MGI:7451032
Gene symbol: Sp7
Gene name: Sp7 transcription factor 7
Probe: Osx probe
Probe preparation: Antisense labelled with P33 RNA
Results
Specimen 4C ctrl: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: forelimb cartilage condensation hypertrophic chondrocyte Present Regionally restricted 4C ctrl Expression is in terminal hypertrophic chondrocytes.
TS22: perichondrium osteoblast Present Regionally restricted 4C ctrl Expression is in differentiating osteoblasts of the perichondrium/periosteum flanking the hypertrophic region.
TS22: periosteum osteoblast Present Regionally restricted 4C ctrl Expression is in differentiating osteoblasts of the perichondrium/periosteum flanking the hypertrophic region.

Specimen 4C -/-: embryonic day 14.5; Ano6tm1Avor/Ano6tm1Avor (more )
Structure Level Pattern Image Note
TS22: forelimb cartilage condensation Present 4C -/- Expression in this mutant is similar to controls.
TS22: perichondrium Present 4C -/- Expression in this mutant is similar to controls.
TS22: periosteum Present 4C -/- Expression in this mutant is similar to controls.

Specimen not shown ctrl: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: forelimb cartilage condensation hypertrophic chondrocyte Present Regionally restricted Expression is in terminal hypertrophic chondrocytes.
TS24: perichondrium osteoblast Present Regionally restricted Expression is in differentiating osteoblasts of the perichondrium/periosteum flanking the hypertrophic region.
TS24: periosteum osteoblast Present Regionally restricted Expression is in differentiating osteoblasts of the perichondrium/periosteum flanking the hypertrophic region.

Specimen not shown -/-: embryonic day 16.5; Ano6tm1Avor/Ano6tm1Avor (more )
Structure Cell Type Level Pattern Image Note
TS24: forelimb cartilage condensation hypertrophic chondrocyte Present Regionally restricted Expression in this mutant is similar to controls.
TS24: perichondrium osteoblast Present Regionally restricted Expression in this mutant is similar to controls.
TS24: periosteum osteoblast Present Regionally restricted Expression in this mutant is similar to controls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory