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Gene Expression Data
Assay Details
Assay
Reference: J:324296 Bell N, et al., Overexpression of transcription factor FoxA2 in the developing skeleton causes an enlargement of the cartilage hypertrophic zone, but it does not trigger ectopic differentiation in immature chondrocytes. Bone. 2022 Apr 6;160:116418
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7450976
Gene symbol: Foxa1
Gene name: forkhead box A1
Antibody: anti-FOXA1 (ab23738)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1a1: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: limb pre-cartilage condensation Absent 1a1 No expression in chondrogenic condensations.
Specimen 1b1: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: limb cartilage condensation Strong Regionally restricted 1b1 Highly expressed in hypertrophic zone. Very little expression elsewhere.
Specimen 1c1: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: limb long bone Strong Regionally restricted 1c1 Highly expressed in hypertrophic zone. Very little expression elsewhere.
Specimen 1c1.1: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: long bone metaphysis Absent 1c1.1 No expression in metaphyseal bone.
Specimen 1c1.2: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate hypertrophic zone Strong 1c1.2
Specimen 1c1.3: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate proliferative zone Absent 1c1.3
Specimen 1c1.4: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate resting zone Absent 1c1.4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory