Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp
Name:	transgene insertion 1, Luis F Parada
MGI ID:	MGI:7449234
Synonyms:	CGD
Transgene:	Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp  Location: unknown
Alliance:	Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Epitope tag, Inducible, Inserted expressed sequence, Recombinase, Reporter) Mutation:    Insertion   Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human HBEGF (1839) Hbegf  (MGI:96070)   Tg(Nes-cre/ERT2,-EGFP,-HBEGF)1Lfp expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Nes (MGI:101784)   Mutation details: The 5.6 kb of the rat 5' regulatory element followed by CreERT2, histone 2B tagged enhanced GFP, and human diphtheria toxin receptor (CGD), each element separated by p2A sequences, and 668bp of the inverted second intron were used to express three proteins from one transcript in neural stem cells. Twenty-nine transgenic founder lines were identified. A single founder that displayed the specific expression pattern without detectable ectopic expression was established. (J:299260)

Activity:	Tissue activity of this recombinase allele
Driver:	Nes (mouse) Summary of all recombinase alleles driven by Nes. Comparative matrix view of recombinase activities Alliance mouse Nes gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:299260 Xie XP, et al., High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31448-31458
All:	2 reference(s)