Gene Expression Data
Assay Details
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Assay
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Reference:
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J:334015
Yoshioka H, et al., Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures. J Bone Miner Metab. 2022 Sep;40(5):839-852
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7448502
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Gene symbol:
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Col1a2
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Gene name:
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collagen, type I, alpha 2
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Results
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Specimen
4a CTL:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Tfamtm1Lrsn/Tfamtm1Lrsn
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Age:
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postnatal day 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: humerus |
Present |
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4a CTL (right)
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4a CTL (left)
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Specimen
4a cKO:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL/J
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Mutant Allele(s):
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Tfamtm1Lrsn/Tfamtm1Lrsn
Tg(Prrx1-cre)1Cjt/0
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Age:
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postnatal day 6
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: humerus |
Weak |
Regionally restricted |
4a cKO (left)
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4a cKO (right)
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Expression markedly reduced, particularly in cortical bone, compared with control.
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Analysis Tools
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