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Gene Expression Data
Assay Details
Assay
Reference: J:236440 You L, et al., The chromatin regulator Brpf1 regulates embryo development and cell proliferation. J Biol Chem. 2015 May 1;290(18):11349-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7447066
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: Fixation was with 12% glacial acetic acid.
Results
Specimen 2A Control: embryonic day 9.5; Brpf1tm1c(EUCOMM)Wtsi/Brpf1+ (more )
Structure Level Pattern Image Note
TS15: vascular element Present Regionally restricted 2A Control Expression in hierarchically organized vascular network.

Specimen 2A Brpf1 delta/delta: embryonic day 9.5; Brpf1tm1c(EUCOMM)Wtsi/Brpf1tm1c(EUCOMM)Wtsi, Tg(EIIa-cre)C5379Lmgd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: vascular element Present Regionally restricted 2A Brpf1 delta/delta Authors report vasculature was not well-formed.

Specimen 2B: embryonic day 9.5; Brpf1tm1c(EUCOMM)Wtsi/Brpf1+ (more )
Structure Level Pattern Image Note
TS15: trunk blood vessel Present Regionally restricted 2B Expression in hierarchically organized vascular network.

Specimen 2C Control: embryonic day 10.5; Brpf1tm1c(EUCOMM)Wtsi/Brpf1+ (more )
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present Regionally restricted 2C Control Expression in branching vessels.

Specimen 2C Brpf1 delta/delta: embryonic day 10.5; Brpf1tm1c(EUCOMM)Wtsi/Brpf1tm1c(EUCOMM)Wtsi, Tg(EIIa-cre)C5379Lmgd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: yolk sac blood vessel Present Regionally restricted 2C Brpf1 delta/delta Authors report vasculature was not well-organized.

Specimen 2D Control: embryonic day 10.5; Brpf1tm1c(EUCOMM)Wtsi/Brpf1+ (more )
Structure Level Pattern Image Note
TS17: chorionic plate Present Regionally restricted 2D Control Expression in branching vessels.

Specimen 2D Brpf1 delta/delta: embryonic day 10.5; Brpf1tm1c(EUCOMM)Wtsi/Brpf1tm1c(EUCOMM)Wtsi, Tg(EIIa-cre)C5379Lmgd/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: chorionic plate Present Regionally restricted 2D Brpf1 delta/delta Authors report vasculature was not well-organized.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory