Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Il17atm1.1(EYFP/cre)Ehs
Name:	interleukin 17A; targeted mutation 1.1, National Institute of Environmental Health Science
MGI ID:	MGI:7446997
Synonyms:	IL-17A-Cre, Il17a(cre/YFP)
Gene:	Il17a  Location: Chr1:20801129-20804720 bp, + strand  Genetic Position: Chr1, 6.45 cM, cytoband A
Alliance:	Il17atm1.1(EYFP/cre)Ehs page

Germline Transmission:	Earliest citation of germline transmission: J:307726
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Recombinase, Reporter) Mutation:    Insertion   Il17atm1.1(EYFP/cre)Ehs expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Il17a (MGI:107364)   Mutation details: generated by targeted insertion of an internal ribosome entry site (IRES) and DNA encoding a Cre recombinase/YFP fusion protein into the 39 untranslated region of the IL-17A gene. (J:307726)

Activity:	Tissue activity of this recombinase allele
Driver:	Il17a (mouse) Summary of all recombinase alleles driven by Il17a. Alliance mouse Il17a gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il17a Mutation:	22 strains or lines available

Original:	J:307726 Shalaby KH, et al., Pathogenic TH17 inflammation is sustained in the lungs by conventional dendritic cells and Toll-like receptor 4 signaling. J Allergy Clin Immunol. 2018 Oct;142(4):1229-1242.e6
All:	2 reference(s)