Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(CAG-flpe)41Ito
Name:	transgene insertion 41, Shigeyoshi Itohara
MGI ID:	MGI:7444773
Synonyms:	CAG-FLPe
Transgene:	Tg(CAG-flpe)41Ito  Location: unknown
Alliance:	Tg(CAG-flpe)41Ito page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(CAG-flpe)41Ito expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note chicken CAG   Mutation details: The CAG promoter (chicken beta-actin promoter with CMV enhancers) was used to drive expression of a gene encoding nuclear localized FLPe recombinase. Five founder lines were established (lines 16, 32, 36, 37 and 41), of which lines 16, 32 and 36 exhibited 100% recombination when crossed to a mouse bearing a frt-flanked cassette; 10/11 mice of line 37 showed recombination. Mosaicism was noted in 2/9 of line 16 and in 1/8 of line 32 double transgenic mice. (J:108559)

Activity:	Tissue activity of this recombinase allele
Driver:	CAG (chicken) Summary of all recombinase alleles driven by CAG.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:108559 Kanki H, et al., High-efficiency CAG-FLPe deleter mice in C57BL/6J background. Exp Anim. 2006 Apr;55(2):137-41
All:	1 reference(s)