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Gene Expression Data
Assay Details
Assay
Reference: J:274134 Javali A, et al., Co-expression of Tbx6 and Sox2 identifies a novel transient neuromesoderm progenitor cell state. Development. 2017 Dec 15;144(24):4522-4529
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7444498
Gene symbol: Tbx6
Gene name: T-box 6
Reporter: YFP
Antibody: anti-GFP
Results
Specimen 3C: embryonic day 9.5; Tbx6tm2Pa/Tbx6+ (more )
Note: Triple labeled: gray - Tbx6 reporter; green - Tbx6 (assay MGI:7444490); red - Sox2 (assay MGI:7444491).
Structure Level Pattern Image Note
TS15: tail Present Regionally restricted 3C merge , 3C YFP Expression was detected in neuromesoderm progenitors.
Specimen 4B Tbx6YFP/+: embryonic day 9.5; Tbx6tm2Pa/Tbx6+ (more )
Note: Double labeled: green - Tbx6 reporter; red - Sox2 (assay MGI:7444491).
Structure Level Pattern Image Note
TS15: tail Present 4B Tbx6YFP/+ merge left , 4B Tbx6YFP/+ merge right , 4B Tbx6YFP/+ YFP(GFP) Co-expression of YFP with Sox2 was 28% in the heterozygote chordo-neural hinge.
Specimen 4B Tbx6YFP/YFP: embryonic day 9.5; Tbx6tm2Pa/Tbx6tm2Pa (more )
Note: Double labeled: green - Tbx6 reporter; red - Sox2 (assay MGI:7444491).
Structure Level Pattern Image Note
TS15: tail Present 4B Tbx6YFP/YFP merge left , 4B Tbx6YFP/YFP YFP(GFP) , 4B Tbx6YFP/YFP merge right A 74% overlap of YFP with Sox2 expression was detected in the mutant chordo-neural hinge.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory