About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:274134 Javali A, et al., Co-expression of Tbx6 and Sox2 identifies a novel transient neuromesoderm progenitor cell state. Development. 2017 Dec 15;144(24):4522-4529
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7444498
Gene symbol: Tbx6
Gene name: T-box 6
Reporter: YFP
Antibody: anti-GFP
Results
Specimen 3C: embryonic day 9.5; Tbx6tm2Pa/Tbx6+ (more )
Note: Triple labeled: gray - Tbx6 reporter; green - Tbx6 (assay MGI:7444490); red - Sox2 (assay MGI:7444491).
Structure Level Pattern Image Note
TS15: tail Present Regionally restricted 3C merge , 3C YFP Expression was detected in neuromesoderm progenitors.
Specimen 4B Tbx6YFP/+: embryonic day 9.5; Tbx6tm2Pa/Tbx6+ (more )
Note: Double labeled: green - Tbx6 reporter; red - Sox2 (assay MGI:7444491).
Structure Level Pattern Image Note
TS15: tail Present 4B Tbx6YFP/+ merge left , 4B Tbx6YFP/+ merge right , 4B Tbx6YFP/+ YFP(GFP) Co-expression of YFP with Sox2 was 28% in the heterozygote chordo-neural hinge.
Specimen 4B Tbx6YFP/YFP: embryonic day 9.5; Tbx6tm2Pa/Tbx6tm2Pa (more )
Note: Double labeled: green - Tbx6 reporter; red - Sox2 (assay MGI:7444491).
Structure Level Pattern Image Note
TS15: tail Present 4B Tbx6YFP/YFP merge left , 4B Tbx6YFP/YFP YFP(GFP) , 4B Tbx6YFP/YFP merge right A 74% overlap of YFP with Sox2 expression was detected in the mutant chordo-neural hinge.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory