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Gene Expression Data
Assay Details
Assay
Reference: J:325730 Ahuja N, et al., Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7444035
Gene symbol: Foxa1
Gene name: forkhead box A1
Antibody: Anti-HNF-3alpha (Q-6; sc-101058)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 6G: embryonic day 15.5 (more )
Note: Double labeled: red - Foxa1; green - Nfatc1 (assay MGI:7444038).
Structure Level Pattern Image Note
TS23: semilunar valve Ambiguous 6G' , 6G
Specimen 6H: embryonic day 15.5; Cyp26b1em1Oncl/Cyp26b1em1Oncl (more )
Note: Double labeled: red - Foxa1; green - Nfatc1 (assay MGI:7444038).
Structure Level Pattern Image Note
TS23: semilunar valve Present Regionally restricted 6H' , 6H Expression increased in the mutant semilunar valve endothelium.
Specimen S7C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: aortic valve Present S7C' , S7C
Specimen S7D: embryonic day 18.5; Cyp26b1em1Oncl/Cyp26b1em1Oncl (more )
Structure Cell Type Level Pattern Image Note
TS26: aortic valve cardiac mesenchymal cell Present S7D' , S7D Expression was dramatically increased in the mutant compared with wild type in both endothelial and mesenchymal cells.
TS26: aortic valve valve endothelial cell Present S7D' , S7D Expression was dramatically increased in the mutant compared with wild type in both endothelial and mesenchymal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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