Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Cxcr5em1(cre/ERT2)Yhar
Name:	C-X-C motif chemokine receptor 5; endonuclease-mediated mutation 1, Yohsuke Harada
MGI ID:	MGI:7443960
Synonyms:	Cxcr5CreERT2
Gene:	Cxcr5  Location: Chr9:44423084-44437741 bp, - strand  Genetic Position: Chr9, 24.84 cM
Alliance:	Cxcr5em1(cre/ERT2)Yhar page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Cxcr5em1(cre/ERT2)Yhar expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Cxcr5 (MGI:103567)     Using the CRISPR/Cas9 system, the P2A sequence and CreERT2 was inserted into the Cxcr5 3'UTR. (J:270146)

Activity:	Tissue activity of this recombinase allele
Driver:	Cxcr5 (mouse) Summary of all recombinase alleles driven by Cxcr5. Comparative matrix view of recombinase activities Alliance mouse Cxcr5 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cxcr5 Mutation:	25 strains or lines available

Original:	J:270146 Takebe T, et al., A novel mouse model for tracking the fate of CXCR5-expressing T cells. Biochem Biophys Res Commun. 2018 Jan 8;495(2):1642-1647
All:	1 reference(s)