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Gene Expression Data
Assay Details
Assay
Reference: J:325730 Ahuja N, et al., Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95
Assay type: RNA in situ
MGI Accession ID: MGI:7443160
Gene symbol: Fzd10
Gene name: frizzled class receptor 10
Probe: IMAGE clone 40090826
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: atrioventricular endocardial cushion Weak Regionally restricted 3F Low expression was detected throughout the valve endothelium and mesenchyme.

Specimen 3G: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: atrioventricular valve Present Regionally restricted 3G Expression was highly enriched in the fibrosa side of the valve. At this later stage, no expression was detected in ventricularis endothelium or within the valve mesenchyme.
TS22: atrioventricular valve valve endothelial cell Present 3G
TS22: atrioventricular valve cardiac mesenchymal cell Present Regionally restricted 3G Expression was detected in the outer mesenchymal cells.

Specimen 3H: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: semilunar valve Present Regionally restricted 3H Expression was highly enriched in the fibrosa side of the valve. At this later stage, no expression was detected in ventricularis endothelium or within the valve mesenchyme.
TS22: semilunar valve valve endothelial cell Present 3H
TS22: semilunar valve cardiac mesenchymal cell Present Regionally restricted 3H Expression was detected in the outer mesenchymal cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory