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Tg(Pdpn-TK)SRkl
Transgene Detail
Summary
Symbol: Tg(Pdpn-TK)SRkl
Name: transgene insertion, Raghu Kalluri
MGI ID: MGI:7442952
Synonyms: PDPN-tk, Tg(PDPN-TK)#Rkl
Transgene: Tg(Pdpn-TK)SRkl  Location: unknown  
Alliance: Tg(Pdpn-TK)SRkl page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation details: A 4-kb mouse Pdpn promoter sequence ligated to the thymidine kinase structural gene from the herpes simplex virus recombinase sequence. Founder line S was used. (J:101977, J:269567)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:269567 Chen Y, et al., Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis. PLoS Biol. 2018 Dec;16(12):e2005907
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory